Caring for age-related hair loss can be retracted, scientists have declared themselves in connection with a new medical breakthrough.
The researchers believe that they have discovered how to reverse the process of gradual baldness, successfully restoring hair on wounded skin.
Scientists from the New York School of Medicine activated a path in the brain called the sonic hedgehog.
This path is very active, while the babies are in the womb and hair follicles are formed, but they are stalled in the elderly or wounded skin.
Researchers believe they have discovered how to reverse the process of gradual baldness, successfully restoring hair on wounded skin.
Figures show that about a quarter of men start to go bald by the time they turn 25, and Prince William starts thinner than all 22.
According to the American Academy of Dermatology, women can also suffer from 40% of women with visible hair loss.
The study examined damaged skin in laboratory mice, focusing on cells called fibroblasts that release collagen.
Collagen is the protein most responsible for maintaining the shape and strength of skin and hair.
Researchers have also focused on fibroblasts because it is known that cells help direct some of the biological processes involved in healing.
The team, led by Dr. Mayumi Ito, activated the hedgehog's sound transmission signal, which is used by the cells to communicate with each other.
By igniting the connection between these cells, hair growth was observed for four weeks in mice.
According to a study published in Nature Communications magazine, hair roots and stem structures began to appear after nine weeks.
Scientists have so far assumed that the scarring and accumulation of collagen in damaged skin was due to its inability to grow hair. But this evidence sheds new light.
What causes hair loss?
Hair loss is common, about 25 percent of men begin to become bald by the time they are 25, reports The American Hair Loss Association.
It is estimated that eight million women in the UK are currently suffering from a degree of hair loss, according to a study of 2,000 women by cosmetic giant L & O 39.
The most common type of hair loss can be caused by life-related events, such as moving home, losing or becoming pregnant, which leads to a general thinning of the hair.
The Yo-yo diet, the birth control pill, stress, eating disorders, chemicals for drugs in the water and modern pesticides in food are also associated with hair loss.
With most of them, hair loss is temporary and may help.
Nutritionists can say that if the level of nutrients is low, it will be expressed through hair. Hair follicles embedded in the scalp should be surrounded by a rich blood supply to ensure adequate nutrition.
Dermatologists suggest that bizarre diets usually lead to iron deficiency, as this can prevent red meat. Vegetarians or vegans with a low content of vitamin B12 and zinc may be prone to hair loss.
Studies show that thinning hair is also associated with progestogens, a synthetic form of progesterone found in replacement and hormone replacement therapy.
Dr. Ito said: “Now we know that this is a signaling problem in cells that are very active when we develop in the uterus, but, nevertheless, in mature skin cells as we age
"Our results show that stimulating fibroblasts through the hedgehog's sonic pathway can provoke hair growth, which was not previously observed during wound healing."
Restoring the legs on damaged skin is an unmet medical need, said Dr. Ito because of the deformity that thousands of people suffer from injuries, burns and other injuries.
She added that this is not only progress for the wounded, but also evidence that improves hair growth in mature skin, she added.
This can help in finding the best medicine for hair regrowth.
Other experiments that included the hedgehog's sonic pathway revealed a higher risk of tumors.
To avoid these risks, the team included only fibroblasts located directly below the surface of the skin, where the roots of the hair follicles (dermal papillae) first appear.
With successful results, Dr. Ito said that this suggests that this barrier may have been overcome, bringing science closer to true skin renewal after injury.
The goal of the doctors is to determine the likely targets for hair regrowth. Currently, licensed drugs can have side effects.
Minoxidil, an over-the-counter skin or lotion, works by increasing blood flow to the scalp, nourishing hair follicles.
It helps about two thirds of patients, men and women, but can have side effects, ranging from rapid beating and swelling of legs and abdominal pain.
Finasteride is available only on an individual prescription for men. It works by blocking an enzyme that converts testosterone to dihydrotestosterone (DHT), another form of hormone that causes baldness.
Studies show that finasteride causes hair growth in 80% of men, but one out of 60 is experiencing impotence – and the risks increase longer than you do on drugs.