According to the work gathered in these specialized media, a team from the Institute of Life and Health Sciences at the University of Kyoto (Japan) has done serious research on how cells behave to model, stretch and expand tissues, which would make it easier to mechanical creation of complete organs.
In particular, the researchers focused on the generation of the eye and how the spherical shape is formed.
“Although our study shows the ability to control the forms of organs made in vitro — using appropriate mechanical stimuli and based on predictions — existing methods are still limited,” said the main researcher of the Mototsugu Eiraku project in statements collected by Scientific Achievements.
Another writer, Saturo Okuda, explained that until now, the grounds that force each cell to modulate itself in order to ultimately create a silhouette of an organ have been “uncertain”.
The experts developed a computer simulation system that calculates the formation of tissue structures in three dimensions, on the basis of which they created a virtual eye, thanks to which they could predict the process of cellular formation of a sphere.
Based on this and applying it in the cells of mice, the researchers mechanically strained specific points of the cells, obtaining the expected effect when changing the shape of the tissue on the basis of predictions.