Thursday , January 21 2021

Mannose sugar, a new hope for fighting cancer – BBC News

The body cannot live without glucose. Blood sugar is part of what feeds our tissues to grow. The problem is that cancer cells also use it to spread. Now scientists believe that they have found a way to cut off this supply.

And this is through mannose sugar, natural supplement who tried slow down which are expanding various types of cancer in mice and improved the effects of chemotherapy treatment, according to a study by Cancer Research UK and Cancer Reasearch Worldwide, published this week in a scientific journal nature,

Although the results were obtained in mice, the scientists responsible for the study hope that they will be used in patients with people, but they need to do more tests, said BBC journalist Alex Terrien.

For the experiment, the research team controlled mannose, a type of sugar that It can be found in fruits such as blueberries., to mice with pancreatic cancer, lung and skin, and found that the growth of tumors slowed down without causing side effects.

Mannose is a natural supplement that can be found in some fruits, such as blueberries.

It is believed that mannose, readily available and sometimes used to treat urinary tract infections, prevents the use of tumors by glucose although the experts who conducted the study warn that no one should take mannose, believing that it will be cured, because they still need to do many more tests.

More affective treatment

Mannose has proven that it not only prevents the growth of certain types of cancer, but also improves the results of certain types of treatment.

In mice that were treated with two of the most commonly used chemotherapeutic drugs, cisplatin and doxorubicin, the researchers found that Mannose treatment strengthened the effects of chemotherapy, reducing the growth rate of a tumor and its size, wrote a BBC health expert.

For other types of cancer, such as leukemia, osteosarcoma (bone cancer), ovarian cancer, and intestines, some cells respond well to mannose, while others do not. Their response seems to depend on the levels that these cells have on the enzyme that destroys this sugar.

DNA acting with a cancer cell.
Mannose has not proven effective in cancers such as leukemia or ovarian cancer.

Lead author, Professor Kevin Ryan from the Institute of Cancer Research. Beatson, told Alex Bill Beery that his team found a dose of mannose, that "can block enough glucose to slow tumor growth in micebut not enough to prevent the growth of normal tissue. "

Organs require glucose for energy, but cancers also use it to stimulate their growth.

“This is an initial investigation, but there is hope that finding this perfect balance means that in the future, Mannose can be administered to cancer patients to improve chemotherapy without compromising their overall health.– He added, recalling the warning that no one should independently supply this natural supplement without consulting with his doctor.

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